Therapy in Acute Phase

• First Line Therapy
• ASA + IVIG
• ASA + INFLIXIMAB
• Add on Therapy for first line Therapy Depends on serverity of CAL
• Antioxidants (Vitamins - ACE)
• Ulinastatin
• Doxicylin
• IVMP

• 2g IVIG/kg BW as single dose over a period of 24hrs
• Aspirin 60-80mg till child become a febrile
• Aspirin treatment should be adjusted to a low dosage when the fever subsides after 48 to 72 h (3 to 5mg/kg/day x 8wks if no CAD)
• With CAL, continue Aspirin and add Clopidogrel 1mg/kg/day max 75mg/d till the resolution of CAD on your Echo follow up
• With Giant aneurysm; Add warfarin/Coumedine/low molecular weight Heparin