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Scoring System
Prediction scoring Systems forIVIG Resistant cases
Kobayashi score ( ≥5 points; sensitivity 76%, specificity 80%)
| NA | ≤133 mmol/L | 2 | |
| AST | ≥100 IU/L | 2 | |
| Day of starting treatment (or diagnosis) | |||
| Day 4 after onset or earlier | 2 | ||
| Neutrophils | ≥80% | 2 | |
| CRP | ≥10 mg/dL | 1 | |
| PLatelets | ≤300,000/μL | 1 | |
| Age (Months) | ≤12 months | 1 | |
Egami score (≥3 points; sensitivity 76%, specificity 80%)
| ALT | ≥80 IU/L | 2 |
| Day of starting treatment (or diagnosis) Day 4 after onset or earlier | 1 | |
| CRP | ≥8 mg/dL | 1 |
| PLatelets | ≤300,000/μL | 1 |
| Age (Months) | ≤1≤6 months | 1 |
Sano score (≥2 points; sensitivity 77%, specificity 86%)
| AST | ≥200 IU/L | 2 |
| Total bilirubin | ≥0.9 mg/D | 1 |
| CRP | ≥7 mg/dL | 1 |
Sathoshi Sato Score (3 or >3)
| Neutrophils | >75% | 2 |
| IL 6 | >140pg/ml | 2 |
| Il-6 | 70-140pg/ml | 1 |